Tapentadol is a prescription medication used to manage moderate to severe acute pain where other treatments may not be sufficient. It is also used in its extended-release form to treat chronic pain, including pain caused by neuropathy in people with diabetes. As an opioid analgesic, Tapentadol works by changing the way the brain and nervous system respond to pain.

Tapentadol is available in both immediate-release (IR) and extended-release (ER) tablets. The immediate-release form is typically used for short-term pain management, with dosages that may be taken every 4 to 6 hours, depending on the intensity of the pain and the medical advice provided. The extended-release form is used for around-the-clock treatment of pain and is not intended for use on an as-needed basis.

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